Epstein-barr virus positive primary sinonasal nasopharyngeal-type undifferentiated carcinoma: a distinct entity
Primary sinonasal nasopharyngeal-type undifferentiated carcinoma (PSNPC) is a rare variant of the sinonasal undifferentiated carcinoma (SNUC). The histological classification has implications on its management. We report a case of a 32 year old lady who presented with progressive nasal obstruction d...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Yuzuncu Yil Universitesi Tip Fakultesi
2017
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| Subjects: | |
| Online Access: | http://eprints.utm.my/id/eprint/76101/1/NikMohdHazleigh2017_Epstein-barrVirusPositivePrimarySinonasal.pdf http://eprints.utm.my/id/eprint/76101/ https://www.journalagent.com/ejm/pdfs/EJM-76486-CASE_REPORT-ZAHEDI.pdf |
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| Institution: | Universiti Teknologi Malaysia |
| Language: | English |
| Summary: | Primary sinonasal nasopharyngeal-type undifferentiated carcinoma (PSNPC) is a rare variant of the sinonasal undifferentiated carcinoma (SNUC). The histological classification has implications on its management. We report a case of a 32 year old lady who presented with progressive nasal obstruction due to a sinonasal tumour. Endoscopic excision was performed and examination confirmed PSNPC with positive Epstein Barr virus in-situ hybridisation. Identification and recognition of PSNPC as a separate clinicopathological entity from SNUC is important as it dictates the management of this rare variant. Immunohistochemical analysis is invaluable in this endeavor. |
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