A Systematic Review on the Efficacy of Common Antacid Components
Gastroesophageal Reflux Disease (GERD) is a common health issue worldwide that utilizes antacids to mitigate its symptoms such as chest pains and burning sensations. However, the most common component used in antacids, Aluminum Hydroxide, has a high toxicity level as it builds up in the body. Thus,...
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| Main Authors: | , , , |
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| Format: | text |
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Animo Repository
2021
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| Online Access: | https://animorepository.dlsu.edu.ph/conf_shsrescon/2021/paper_fnh/4 https://animorepository.dlsu.edu.ph/context/conf_shsrescon/article/1617/viewcontent/FNH_A_Systematic_Review_on_the_Efficacy_of_Common_Antacid_Components.pdf |
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| Institution: | De La Salle University |
| Summary: | Gastroesophageal Reflux Disease (GERD) is a common health issue worldwide that utilizes antacids to mitigate its symptoms such as chest pains and burning sensations. However, the most common component used in antacids, Aluminum Hydroxide, has a high toxicity level as it builds up in the body. Thus, this study aims to determine whether Alginate, an organic compound, and Calcium Carbonate, which is considered an age-friendly component, are suitable antacid component alternatives to Aluminum Hydroxide in terms of their corresponding Acid Neutralization Capacity (ANC) and adverse effects. The researchers utilized a systematic review approach, guided by the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P), to accomplish the study objectives. The study results suggest that Calcium Carbonate has the highest ANC while Alginate has the second-highest ANC and has fewer adverse effects than placebo. These results support the claim that Alginate and Calcium Carbonate are suitable alternatives to Aluminum Hydroxide. |
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