Synthesis of antimicrobial TAT multimers

• Main Author: Chiongson, Justin Brian
• Format: text
• Language: English
• Published: Animo Repository 2019
• Subjects: Peptides > Synthesis; Anti-infective agents; Amino Acids, Peptides, and Proteins; Cells; Medicine and Health Sciences
• Online Access: https://animorepository.dlsu.edu.ph/etd_masteral/5839
• Institution: De La Salle University

Cell penetrating peptides (CPP) are short cationic peptides that offer therapeutic use as drug cargoes through their innate ability to permeate the cell membrane. The tridecapeptide (GRKKRRQRRRPPQ) is a known sequence from the 86 to 102 amino acid long protein from the human immunodeficiency virus (...