Substrate screening for a novel condensation of imines: New approach towards a "click" type reaction for bioconjugation
An unprecedented condensation reaction of N-benzylimines was applied to the bioconjugation of lysine residues. A second-generation lysine dendrimer 14 with four ε-amino groups was prepared as the model peptide using solid-supported methods. The dendrimer 14 reacted with N-benzylimine 8 in DMF, which...
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| Format: | text |
| Language: | English |
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Animo Repository
2011
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| Online Access: | https://animorepository.dlsu.edu.ph/etd_masteral/6626 https://animorepository.dlsu.edu.ph/cgi/viewcontent.cgi?article=12995&context=etd_masteral |
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| Institution: | De La Salle University |
| Language: | English |