Substrate screening for a novel condensation of imines: New approach towards a "click" type reaction for bioconjugation

An unprecedented condensation reaction of N-benzylimines was applied to the bioconjugation of lysine residues. A second-generation lysine dendrimer 14 with four ε-amino groups was prepared as the model peptide using solid-supported methods. The dendrimer 14 reacted with N-benzylimine 8 in DMF, which...

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Bibliographic Details
Main Author: Janairo, Jose Isagani B.
Format: text
Language:English
Published: Animo Repository 2011
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Online Access:https://animorepository.dlsu.edu.ph/etd_masteral/6626
https://animorepository.dlsu.edu.ph/cgi/viewcontent.cgi?article=12995&context=etd_masteral
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Institution: De La Salle University
Language: English
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