An in silico analysis of the binding affinity of alliin from Allium sativum L. targeting HMGB-1 and IL-6 inflammatory cascade

• المؤلفون الرئيسيون: Cuabo, Rejie May M., Gabia, Katherine F., Palaypay, Alyssa Bianca F., Roque, Glen Andrei R.
• التنسيق: text
• اللغة: English
• منشور في: Animo Repository 2024
• الموضوعات: Garlic; HMGB proteins; Interleukin-6; Biology
• الوصول للمادة أونلاين: https://animorepository.dlsu.edu.ph/etdb_bio/62
• المؤسسة: De La Salle University

Alcoholic liver disease (ALD) is a spectrum of disease related to excessive intake of alcohol. One of its stages is alcoholic hepatitis (AH) which occurs through severe inflammation of the liver. It has been known that AH is induced by many mechanisms and one of which is endotoxemia. Excessive consu...