Synthesis of cholic acid-terminated dendritic lysine-block-poly(ehtylyne glycol)-block-dendritic lysine and its enhanced ability to solubilize pacliltaxel in water
Paclitaxel, a chemotherapeutic drug used to inhibit mitosis in cancer cells, requires the use of the solubilizer Cremophor EL due to its poor water solubility. However, Cremophor EL is associated with adverse reactions following chemotherapy. This work reports the synthesis of an alternative solubil...
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| Main Authors: | , |
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| Format: | text |
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Animo Repository
2018
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| Online Access: | https://animorepository.dlsu.edu.ph/faculty_research/11272 |
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| Institution: | De La Salle University |