Peroxisome proliferator-activated receptor gamma as a theragnostic target for mesenchymal-type glioblastoma patients

• المؤلفون الرئيسيون: Hua, Tuyen N. M., Oh, Jiwoong, Kim, Sohyun, Antonio, Jayson M., Vo, Vu T. A., Om, Jiyeon, Choi, Jong-Whan, Kim, Jeong-Yub, Jung, Chan-Woong, Park, Myung-Jin, Jeong, Yangsik
• التنسيق: text
• منشور في: Animo Repository 2020
• الموضوعات: Peroxisomes; Glioblastoma multiforme—Treatment; Nervous System Diseases
• الوصول للمادة أونلاين: https://animorepository.dlsu.edu.ph/faculty_research/11240
• المؤسسة: De La Salle University

Glioblastomas (GBMs) are characterized by four subtypes, proneural (PN), neural, classical, and mesenchymal (MES) GBMs, and they all have distinct activated signaling pathways. Among the subtypes, PN and MES GBMs show mutually exclusive genetic signatures, and the MES phenotype is, in general, belie...