Dengue virus activates polyreactive, natural IgG B cells after primary and secondary infection

• Main Authors: Balakrishnan, Thavamalar, Bela-ong, Dennis B., Toh, Ying Xiu, Flamand, Marie, Devi, Shamala, Koh, Mickey B., Hibberd, Martin L., Ooi, Eng Eong, Low, Jenny G., Leo, Yee Sin, Gu, Feng, Fink, Katja
• Format: text
• Published: Animo Repository 2011
• Subjects: Dengue viruses; Dengue; Immunoglobulin G; Virus Diseases
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/11558
• Institution: De La Salle University

Background: Dengue virus is transmitted by mosquitoes and has four serotypes. Cross-protection to other serotypes lasting for a few months is observed following infection with one serotype. There is evidence that low-affinity T and/or B cells from primary infections contribute to the severe syndrome...