Synthesis and characterization of pyrazinamide derivative of Imidazo[2,1-b][1,3,4]thiadiazole, a potential anti-tubercolosis drug

• Main Authors: Dela Cruz, Derrick Emjae Gabriel T., Eslava, Sheilu G., Alea, Glenn V., Ajero, Michael Dominic M., Lagua, Faith Marie G.
• Format: text
• Published: Animo Repository 2019
• Subjects: Imidazoles—Derivatives; Antitubercular agents; Pyrazinamide; Chemicals and Drugs
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/11447
• Institution: De La Salle University

Despite the availability of first- and second-line drugs for the treatment of tuberculosis, the increasing prevalence of multi-drug resistance and extensively drug-resistant strains of Mycobacterium tuberculosis still poses a major threat to global health. With this, researchers are motivated to des...