Computer-aided screening for potential inhibitory compounds against a Klebsiella pneumoniae local isolate containing SHV-1 and CTX-M antibiotic resistance genes

• Main Authors: Castro, Anna, Sy, Jamie Bernadette, Macalino, Stephani Joy Y., Morales, Nadia, Abid, Princess Alyssa, Billones, Junie, Carrillo, Maria Constancia
• Format: text
• Published: Animo Repository 2021
• Subjects: Klebsiella pneumoniae; Anti-infective agents; Medicinal-Pharmaceutical Chemistry
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/11454
• Institution: De La Salle University

Extended-spectrum beta-lactamases (ESBLs) allow bacteria to become resistant to commonly used antibiotics especially in common pathogens such as Klebsiella pneumoniae. ESBLs are a significant public health concern as their presence severely limits treatment options. Discovery and development of new...