Virtual screening against M. tuberculosis 7,8-diaminopelargonic acid synthase (MtbBioA) and in silico toxicity evaluation of top hits

• Main Authors: Billones, Junie B., Carrillo, Maria Constancia O., Organo, Voltaire G., Macalino, Stephani Joy Y., Emnacen, Inno A., Sy, Jamie Bernadette A.
• Format: text
• Published: Animo Repository 2014
• Subjects: Mycobacterium tuberculosis; Biotin; Medicinal-Pharmaceutical Chemistry
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/11459
• Institution: De La Salle University

Tuberculosis (TB) remains to be one of the major public health concerns worldwide. The continuing emergence of Mtb strains resistant to known drugs makes the campaign for successful TB control and treatment very difficult to accomplish. It is therefore imperative to search for newer chemical entitie...