Interferon-α and -β restrict polyomavirus JC replication in primary human fetal glial cells: Implications for progressive multifocal leukoencephalopathy therapy

• المؤلفون الرئيسيون: Go, Juliene Kimberly G., Verma, Saguna, Gurjav, Ulziijargal, Sumibcay, Laarni, Nerurkar, Vivek R.
• التنسيق: text
• منشور في: Animo Repository 2007
• الموضوعات: Interferon; Polyomaviruses; Neuroglia; Immunology and Infectious Disease
• الوصول للمادة أونلاين: https://animorepository.dlsu.edu.ph/faculty_research/13185

One of the major limitations of highly active antiretroviral therapy is its inability to inhibit the replication of polyomavirus JC (JCV), the etiologic agent of progressive multifocal leukoencephalopathy (PML), an acquired immunodeficiency syndrome-defining illness. We previously demonstrated the i...