JC virus induces altered patterns of cellular gene expression: Interferon-inducible genes as major transcriptional targets

• Main Authors: Verma, Saguna, Ziegler, Katja, Ananthula, Praveen, Co, Juliene Kimberly G., Frisque, Richard J., Yanagihara, Richard, Nerurkar, Vivek R.
• Format: text
• Published: Animo Repository 2006
• Subjects: Polyomaviruses; Interferon; Neuroglia; Viruses
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/13184
• Institution: De La Salle University

Human polyomavirus JC (JCV) infects 80% of the population worldwide. Primary infection, typically occurring during childhood, is asymptomatic in immunocompetent individuals and results in lifelong latency and persistent infection. However, among the severely immunocompromised, JCV may cause a fatal...