Induction of innate immune response by SIV in vivo and in vitro: Differential expression and function of RIG-I and MDA5
IFN-P induction occurs during acute SIV infection in the CNS. The pathways that induce IFN-P in SIV-infected macrophages, the major infected cell in the brain, have not been identified. We have examined expression and function of cytosolic RNA sensors, retinoic acid inducible gene I (RIG-I) and mela...
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Format: | text |
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Animo Repository
2011
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Online Access: | https://animorepository.dlsu.edu.ph/faculty_research/13183 |
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Institution: | De La Salle University |