Induction of innate immune response by SIV in vivo and in vitro: Differential expression and function of RIG-I and MDA5

• المؤلف الرئيسي: Co, Juliene Kimberly G.
• التنسيق: text
• منشور في: Animo Repository 2011
• الموضوعات: Simian immunodeficiency virus; Natural immunity; Viruses
• الوصول للمادة أونلاين: https://animorepository.dlsu.edu.ph/faculty_research/13183
• المؤسسة: De La Salle University

IFN-P induction occurs during acute SIV infection in the CNS. The pathways that induce IFN-P in SIV-infected macrophages, the major infected cell in the brain, have not been identified. We have examined expression and function of cytosolic RNA sensors, retinoic acid inducible gene I (RIG-I) and mela...