Chemical constituents of andrographis paniculata (Burm.f.) nees
Chemical investigation of the dichloromethane extracts of Andrographis paniculata (Burm.f.) Nees led to the isolation of andrographolide (1), 14-deoxyandrographolide (2), 14-deoxy-12-hydroxyandrographolide (3), a mixture of β-sitosterol (4a) and stigmasterol (4b) in a 3:1 ratio, and chlorophyll a (5...
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| Main Authors: | , , , |
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| Format: | text |
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Animo Repository
2016
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| Online Access: | https://animorepository.dlsu.edu.ph/faculty_research/1160 |
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| Institution: | De La Salle University |
| Summary: | Chemical investigation of the dichloromethane extracts of Andrographis paniculata (Burm.f.) Nees led to the isolation of andrographolide (1), 14-deoxyandrographolide (2), 14-deoxy-12-hydroxyandrographolide (3), a mixture of β-sitosterol (4a) and stigmasterol (4b) in a 3:1 ratio, and chlorophyll a (5) from the leaves; a mixture of 4a and 4b in a 3:2 ratio, 5,2'-dihydroxy-7,8-dimethoxyflavone or skullcapflavone I (6), and a mixture of long chain trans-cinnamate esters (7a) and β-sitosteryl fatty acid esters (7b) from the roots; 4a, monogalactosyl diacylglycerols (8), lupeol (9), and triacylglycerols (10) from the pods; and 2 from the stems. The structures of 1-3 and 6 were elucidated by extensive 1D and 2D NMR spectroscopy, while the structures of 4, 5 and 7-10 were identified by comparison of their NMR data with those reported in the literature. © 2016, International Journal of Pharmacognosy and Phytochemical Research. All right reserved. |
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