Chemical constituents of andrographis paniculata (Burm.f.) nees

Chemical investigation of the dichloromethane extracts of Andrographis paniculata (Burm.f.) Nees led to the isolation of andrographolide (1), 14-deoxyandrographolide (2), 14-deoxy-12-hydroxyandrographolide (3), a mixture of β-sitosterol (4a) and stigmasterol (4b) in a 3:1 ratio, and chlorophyll a (5...

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Main Authors: Tan, Maria Carmen S., Oyong, Glenn G., Shen, Chien Chang, Ragasa, Consolacion Y.
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Published: Animo Repository 2016
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Online Access:https://animorepository.dlsu.edu.ph/faculty_research/1160
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spelling oai:animorepository.dlsu.edu.ph:faculty_research-21592021-05-18T02:19:03Z Chemical constituents of andrographis paniculata (Burm.f.) nees Tan, Maria Carmen S. Oyong, Glenn G. Shen, Chien Chang Ragasa, Consolacion Y. Chemical investigation of the dichloromethane extracts of Andrographis paniculata (Burm.f.) Nees led to the isolation of andrographolide (1), 14-deoxyandrographolide (2), 14-deoxy-12-hydroxyandrographolide (3), a mixture of β-sitosterol (4a) and stigmasterol (4b) in a 3:1 ratio, and chlorophyll a (5) from the leaves; a mixture of 4a and 4b in a 3:2 ratio, 5,2'-dihydroxy-7,8-dimethoxyflavone or skullcapflavone I (6), and a mixture of long chain trans-cinnamate esters (7a) and β-sitosteryl fatty acid esters (7b) from the roots; 4a, monogalactosyl diacylglycerols (8), lupeol (9), and triacylglycerols (10) from the pods; and 2 from the stems. The structures of 1-3 and 6 were elucidated by extensive 1D and 2D NMR spectroscopy, while the structures of 4, 5 and 7-10 were identified by comparison of their NMR data with those reported in the literature. © 2016, International Journal of Pharmacognosy and Phytochemical Research. All right reserved. 2016-08-01T07:00:00Z text https://animorepository.dlsu.edu.ph/faculty_research/1160 Faculty Research Work Animo Repository Acanthaceae--Analysis Chemistry
institution De La Salle University
building De La Salle University Library
continent Asia
country Philippines
Philippines
content_provider De La Salle University Library
collection DLSU Institutional Repository
topic Acanthaceae--Analysis
Chemistry
spellingShingle Acanthaceae--Analysis
Chemistry
Tan, Maria Carmen S.
Oyong, Glenn G.
Shen, Chien Chang
Ragasa, Consolacion Y.
Chemical constituents of andrographis paniculata (Burm.f.) nees
description Chemical investigation of the dichloromethane extracts of Andrographis paniculata (Burm.f.) Nees led to the isolation of andrographolide (1), 14-deoxyandrographolide (2), 14-deoxy-12-hydroxyandrographolide (3), a mixture of β-sitosterol (4a) and stigmasterol (4b) in a 3:1 ratio, and chlorophyll a (5) from the leaves; a mixture of 4a and 4b in a 3:2 ratio, 5,2'-dihydroxy-7,8-dimethoxyflavone or skullcapflavone I (6), and a mixture of long chain trans-cinnamate esters (7a) and β-sitosteryl fatty acid esters (7b) from the roots; 4a, monogalactosyl diacylglycerols (8), lupeol (9), and triacylglycerols (10) from the pods; and 2 from the stems. The structures of 1-3 and 6 were elucidated by extensive 1D and 2D NMR spectroscopy, while the structures of 4, 5 and 7-10 were identified by comparison of their NMR data with those reported in the literature. © 2016, International Journal of Pharmacognosy and Phytochemical Research. All right reserved.
format text
author Tan, Maria Carmen S.
Oyong, Glenn G.
Shen, Chien Chang
Ragasa, Consolacion Y.
author_facet Tan, Maria Carmen S.
Oyong, Glenn G.
Shen, Chien Chang
Ragasa, Consolacion Y.
author_sort Tan, Maria Carmen S.
title Chemical constituents of andrographis paniculata (Burm.f.) nees
title_short Chemical constituents of andrographis paniculata (Burm.f.) nees
title_full Chemical constituents of andrographis paniculata (Burm.f.) nees
title_fullStr Chemical constituents of andrographis paniculata (Burm.f.) nees
title_full_unstemmed Chemical constituents of andrographis paniculata (Burm.f.) nees
title_sort chemical constituents of andrographis paniculata (burm.f.) nees
publisher Animo Repository
publishDate 2016
url https://animorepository.dlsu.edu.ph/faculty_research/1160
_version_ 1701351042353987584