Chemical constituents of Aglaia loheri

The dichloromethane extract of the leaves of Aglaia loheri afforded spinasterol (1), trilinolein (2) and phytyl fatty acid ester (3). The structures of 1-2 were identified by comparison of their 13C NMR data with those reported in the literature. Compounds 1, 2 and 3 were evaluated for cytotoxicity...

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Bibliographic Details
Main Authors: Ragasa, Consolacion Y., Torres, Oscar B., Shen, Chien Chang, Mejia, Michelle Gayle R., Ferrer, Regina Joyce, Jacinto, Sonia D.
Format: text
Published: Animo Repository 2012
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Online Access:https://animorepository.dlsu.edu.ph/faculty_research/1505
https://animorepository.dlsu.edu.ph/context/faculty_research/article/2504/type/native/viewcontent
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Institution: De La Salle University
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Summary:The dichloromethane extract of the leaves of Aglaia loheri afforded spinasterol (1), trilinolein (2) and phytyl fatty acid ester (3). The structures of 1-2 were identified by comparison of their 13C NMR data with those reported in the literature. Compounds 1, 2 and 3 were evaluated for cytotoxicity against the colon carcinoma (HCT 116) using the MTT assay. They exhibited moderate cytotoxicity against HCT 116 with IC50 values of 40.52, 46.73 and 40.06, respectively. © 2012 Pharmacognosy Network Worldwide [Phcog.Net].