Chemical constituents of Aglaia loheri
The dichloromethane extract of the leaves of Aglaia loheri afforded spinasterol (1), trilinolein (2) and phytyl fatty acid ester (3). The structures of 1-2 were identified by comparison of their 13C NMR data with those reported in the literature. Compounds 1, 2 and 3 were evaluated for cytotoxicity...
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Main Authors: | , , , , , |
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Format: | text |
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Animo Repository
2012
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Online Access: | https://animorepository.dlsu.edu.ph/faculty_research/1505 https://animorepository.dlsu.edu.ph/context/faculty_research/article/2504/type/native/viewcontent |
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Institution: | De La Salle University |
Summary: | The dichloromethane extract of the leaves of Aglaia loheri afforded spinasterol (1), trilinolein (2) and phytyl fatty acid ester (3). The structures of 1-2 were identified by comparison of their 13C NMR data with those reported in the literature. Compounds 1, 2 and 3 were evaluated for cytotoxicity against the colon carcinoma (HCT 116) using the MTT assay. They exhibited moderate cytotoxicity against HCT 116 with IC50 values of 40.52, 46.73 and 40.06, respectively. © 2012 Pharmacognosy Network Worldwide [Phcog.Net]. |
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