Chemical constituents and cytotoxicity of the leaves of Dysoxylum gaudichaudianum (A. Juss.) Miq.

• Main Authors: Ragasa, Consolacion Y., Ng, Vincent Antonio S., De Los Reyes, Mariquit M., Mandia, Emelina H., Oyong, Glenn G., Shen, Chien Chang
• Format: text
• Published: Animo Repository 2014
• Subjects: Meliaceae > Analysis; Meliaceae—Toxicity testing; Foliar diagnosis; Chemistry
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/1778
• Institution: De La Salle University

The crude dicloromethane leaf extract of Dysoxylum gaudichaudianum (A. Juss.) Miq. was tested for cytotoxicity against breast cancer (MCF-7) and colon cancer (HT-29) cells and exhibited IC50 values of 7.35 and 13.19 μg/mL, respectively. Chemical investigation of the dichloromethane leaf extract affo...