Bioactive triterpenes from Diospyros blancoi

Bioactive triterpenes from Diospyros blancoi

The ethyl acetate extract of the air-dried leaves of Diospyros blancoi afforded isoarborinol methyl ether (1), a mixture of -amyrin palmitate, -amyrin palmitoleate, -amyrin palmitate and -amyrin palmitoleate (2) in a 13 : 4 : 3 : 1 ratio, and squalene. The structures of 1, 2 and squalene were elucid...

Full description

Saved in:
Bibliographic Details
Main Authors: Ragasa, Consolacion Y., Puno, Marc Rhyan Anthony, Sengson, Josephine Marie Angeline P., Shen, Chien Chang, Rideout, John A., Raga, Dennis D.
Format: text
Published: Animo Repository 2009
Subjects:
Diospyros > Analysis
Amyrin
Analgesics
Anti-inflammatory agents
Anti-infective agents
Ebenaceae
Chemistry
Online Access:https://animorepository.dlsu.edu.ph/faculty_research/1640
https://animorepository.dlsu.edu.ph/context/faculty_research/article/2639/type/native/viewcontent
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: De La Salle University
Description
Summary:The ethyl acetate extract of the air-dried leaves of Diospyros blancoi afforded isoarborinol methyl ether (1), a mixture of -amyrin palmitate, -amyrin palmitoleate, -amyrin palmitate and -amyrin palmitoleate (2) in a 13 : 4 : 3 : 1 ratio, and squalene. The structures of 1, 2 and squalene were elucidated by extensive 1D and 2D NMR spectroscopy. Compounds 1 and 2 exhibited antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, Candida albicans, Staphylococcus aureus and Trichophyton mentagrophytes, and were found inactive against Bacillus subtilis and Aspergillus niger. Sample 2 exhibited significant analgaesic and anti-inflammatory activities.

Similar Items