A bioactive diterpene from Smallanthus sonchifolius
The dichloromethane extract of the air-dried leaves and freeze-dried tubers of Smallanthus sonchifolius afforded ent-kaurenoic acid (1). The structure of 1 was elucidated by extensive 1D and 2D NMR spectroscopy and was found to exhibit significant analgesic and anti-inflammatory activities. Ent-kaur...
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2008
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oai:animorepository.dlsu.edu.ph:faculty_research-26452021-07-13T07:04:05Z A bioactive diterpene from Smallanthus sonchifolius Ragasa, Consolacion Y. Alimboyoguen, Agnes B. Urban, Sylvia Raga, Dennis D. The dichloromethane extract of the air-dried leaves and freeze-dried tubers of Smallanthus sonchifolius afforded ent-kaurenoic acid (1). The structure of 1 was elucidated by extensive 1D and 2D NMR spectroscopy and was found to exhibit significant analgesic and anti-inflammatory activities. Ent-kaurenoic acid (1), dissolved in dimethylsulfoxide, also displayed potential anti-diabetes and anti-toxicity activity. In addition, 1 showed low antimicrobial activities against E. coli, P. aeruginosa, S. aureus, C. albicans and T. mentagrophytes, but was found to be inactive against B. subtilis and A. niger. 2008-01-01T08:00:00Z text text/html https://animorepository.dlsu.edu.ph/faculty_research/1646 https://animorepository.dlsu.edu.ph/context/faculty_research/article/2645/type/native/viewcontent Faculty Research Work Animo Repository Yacon Diterpenes Analgesics Anti-inflammatory agents Compositae Chemistry |
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Philippines Philippines |
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Yacon Diterpenes Analgesics Anti-inflammatory agents Compositae Chemistry |
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Yacon Diterpenes Analgesics Anti-inflammatory agents Compositae Chemistry Ragasa, Consolacion Y. Alimboyoguen, Agnes B. Urban, Sylvia Raga, Dennis D. A bioactive diterpene from Smallanthus sonchifolius |
| description |
The dichloromethane extract of the air-dried leaves and freeze-dried tubers of Smallanthus sonchifolius afforded ent-kaurenoic acid (1). The structure of 1 was elucidated by extensive 1D and 2D NMR spectroscopy and was found to exhibit significant analgesic and anti-inflammatory activities. Ent-kaurenoic acid (1), dissolved in dimethylsulfoxide, also displayed potential anti-diabetes and anti-toxicity activity. In addition, 1 showed low antimicrobial activities against E. coli, P. aeruginosa, S. aureus, C. albicans and T. mentagrophytes, but was found to be inactive against B. subtilis and A. niger. |
| format |
text |
| author |
Ragasa, Consolacion Y. Alimboyoguen, Agnes B. Urban, Sylvia Raga, Dennis D. |
| author_facet |
Ragasa, Consolacion Y. Alimboyoguen, Agnes B. Urban, Sylvia Raga, Dennis D. |
| author_sort |
Ragasa, Consolacion Y. |
| title |
A bioactive diterpene from Smallanthus sonchifolius |
| title_short |
A bioactive diterpene from Smallanthus sonchifolius |
| title_full |
A bioactive diterpene from Smallanthus sonchifolius |
| title_fullStr |
A bioactive diterpene from Smallanthus sonchifolius |
| title_full_unstemmed |
A bioactive diterpene from Smallanthus sonchifolius |
| title_sort |
bioactive diterpene from smallanthus sonchifolius |
| publisher |
Animo Repository |
| publishDate |
2008 |
| url |
https://animorepository.dlsu.edu.ph/faculty_research/1646 https://animorepository.dlsu.edu.ph/context/faculty_research/article/2645/type/native/viewcontent |
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