A bioactive diterpene from Smallanthus sonchifolius

• Main Authors: Ragasa, Consolacion Y., Alimboyoguen, Agnes B., Urban, Sylvia, Raga, Dennis D.
• Format: text
• Published: Animo Repository 2008
• Subjects: Yacon; Diterpenes; Analgesics; Anti-inflammatory agents; Compositae; Chemistry
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/1646; https://animorepository.dlsu.edu.ph/context/faculty_research/article/2645/type/native/viewcontent
• Institution: De La Salle University

The dichloromethane extract of the air-dried leaves and freeze-dried tubers of Smallanthus sonchifolius afforded ent-kaurenoic acid (1). The structure of 1 was elucidated by extensive 1D and 2D NMR spectroscopy and was found to exhibit significant analgesic and anti-inflammatory activities. Ent-kaur...