Angio-suppressive triterpenoids from Ardisia cf. elliptica (subgenus Tinus) on duck (Anas platyrynchosL.) chorioallantoic membrane
The dichloromethane extract of the air-dried leaves of Ardisia cf. elliptica (subgenus Tinus) afforded a mixture of bauerenol (1a), α-amyrin (1b) and β-amyrin (1c). Their structures were identified by NMR spectroscopy. Mixtures of the triterpenes (1a-1c) at ratios of 2:2:1, 2:2:3 and 1:1:1 were test...
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| Main Authors: | , , |
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| Format: | text |
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Animo Repository
2013
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| Online Access: | https://animorepository.dlsu.edu.ph/faculty_research/1724 https://animorepository.dlsu.edu.ph/context/faculty_research/article/2723/type/native/viewcontent |
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| Institution: | De La Salle University |
| Summary: | The dichloromethane extract of the air-dried leaves of Ardisia cf. elliptica (subgenus Tinus) afforded a mixture of bauerenol (1a), α-amyrin (1b) and β-amyrin (1c). Their structures were identified by NMR spectroscopy. Mixtures of the triterpenes (1a-1c) at ratios of 2:2:1, 2:2:3 and 1:1:1 were tested for their angio-suppressive effects on duck chorioallantoic membrane (CAM). All three ratios were found to be effective in restricting inter-capillary length, while 1a-1c (2:2:1) was most effective in reducing branch point density with 100% CAM viability and embryo survivability, suggesting a high impact angio-suppressive potential of 1a-1c (2:2:1). © 2013 China Pharmaceutical University. |
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