Chemical constituents of Artocarpus camansi
The dichloromethane extract of the leaves of Artocarpus camansi afforded friedelinol (1), squalene (2), β-sitosterol (3), stigmasterol (4) and phytol (5), while the stems yielded polyprenol (6), cycloartenol (7) and cycloartenol acetate (8). The structures of 1, 7 and 8 were elucidated by extensive...
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| Main Authors: | , , , , |
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| Format: | text |
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Animo Repository
2013
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| Subjects: | |
| Online Access: | https://animorepository.dlsu.edu.ph/faculty_research/1943 |
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| Institution: | De La Salle University |
| Summary: | The dichloromethane extract of the leaves of Artocarpus camansi afforded friedelinol (1), squalene (2), β-sitosterol (3), stigmasterol (4) and phytol (5), while the stems yielded polyprenol (6), cycloartenol (7) and cycloartenol acetate (8). The structures of 1, 7 and 8 were elucidated by extensive 1D and 2D NMR spectroscopy. The cytotoxicity of these triterpenes were tested using the sulforhodamine B assay against the human cancer cell lines: lung adenocarcinoma A549 cells, stomach adenocarcinoma AGS cells, colon adenocarcinoma HT29 cells and prostate cancer PC3 cells. Results of the study indicated that 1, 7 and 8 are non-cytotoxic against these cell lines. Copyright © 2013, Phcog.Net, Published by Reed Elsevier India Pvt. Ltd. All rights reserved. |
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