Antioxidant sensing by spiropyrans: Substituent effects and NMR spectroscopic studies

• Main Authors: Garcia, Joel E., Addison, J. Bennett, Liu, Stephen Z., Lu, Samuel, Faulkner, Andrea L., Hodur, Blanka M., Balmond, Edward I., Or, Victor W., Yun, Jason H., Trevino, Kimberly, Shen, Bowen, Shaw, Jared T., Frank, Natia L., Louie, Angelique Y.
• Format: text
• Published: Animo Repository 2019
• Subjects: Antioxidants; Nuclear magnetic resonance spectroscopy; Spectrum analysis; Chemistry
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/3795; https://animorepository.dlsu.edu.ph/context/faculty_research/article/4797/type/native/viewcontent/acs.jpcb.9b03424
• Institution: De La Salle University

The development of stimuli-responsive small molecules for probing biologically active antioxidants such as glutathione (GSH) has important ramifications in the detection of oxidative stress. An ideal sensor for biological applications should exhibit sufficient sensitivity and selectivity for detecti...