DFT study on the effect of proximal residues on the: Mycobacterium tuberculosis catalase-peroxidase (katG) heme compound I intermediate and its bonding interaction with isoniazid
Isoniazid (INH) is converted into isonicotinyl radical through its interaction with the catalase-peroxidase (katG) enzyme present in the cells of Mycobacterium tuberculosis (M. tb.), the bacteria that causes the tuberculosis disease. This process is important because resistance of M. tb. cells to IN...
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Format: | text |
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Animo Repository
2019
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Online Access: | https://animorepository.dlsu.edu.ph/faculty_research/4461 |
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Institution: | De La Salle University |