DFT study on the effect of proximal residues on the: Mycobacterium tuberculosis catalase-peroxidase (katG) heme compound I intermediate and its bonding interaction with isoniazid

Isoniazid (INH) is converted into isonicotinyl radical through its interaction with the catalase-peroxidase (katG) enzyme present in the cells of Mycobacterium tuberculosis (M. tb.), the bacteria that causes the tuberculosis disease. This process is important because resistance of M. tb. cells to IN...

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Bibliographic Details
Main Authors: Reyes, Yves Ira A., Franco, Francisco C.
Format: text
Published: Animo Repository 2019
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Online Access:https://animorepository.dlsu.edu.ph/faculty_research/4461
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Institution: De La Salle University