Upregulation of mortalin/mthsp70/Grp75 contributes to human carcinogenesis

Mortalin, also known as mthsp70/GRP75/PBP74, interacts with the tumor suppressor protein p53 and inactivates its transcriptional activation and apoptotic functions. Here, we examined the level of mortalin expression in a large variety of tumor tissues, tumor-derived and in vitro immortalized human c...

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Main Authors: Wadhwa, Renu, Takano, Syuichi, Deocaris, Custer C., Pereira-Smith, Olivia M., Reddel, Roger R., Kaul, Sunil C.
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Published: Animo Repository 2006
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Online Access:https://animorepository.dlsu.edu.ph/faculty_research/5471
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Institution: De La Salle University

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