Collagen extract from chicken skin as clot actovator
This research goals to determine the ability of collagen extracted from chicken skin as a clot activator. It sought to identify the (1) duration of the collagen extract to induce optimum blood clot formation; (2) significant difference between each concentration of the test; and, (3) most effective...
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| Main Authors: | , |
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| Format: | text |
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Animo Repository
2022
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| Online Access: | https://animorepository.dlsu.edu.ph/faculty_research/5995 |
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| Institution: | De La Salle University |
| Summary: | This research goals to determine the ability of collagen extracted from chicken skin as a clot activator. It sought to identify the (1) duration of the collagen extract to induce optimum blood clot formation; (2) significant difference between each concentration of the test; and, (3) most effective concentration as an in vitro clot activator. The collagen was extracted bases on Pacak’s improved method for the preparation of type I collagen from skin and then identified by Van Gieson’s stain. This was then tested on 3 patients at 3 different concentrations 1:30, 1:40 and 1:50 in a triplicate manner. Results show that blood treated with collagen at 1:40 has a lower standard deviation (1.92188) from the control and has fastest clotting time (20.2957) among the thee. On the other hand, Tukey’s post hoc test proved that concentrations at 1:40 and 1:50 both showed effectivity. With this, the researchers reject the null hypotheses, concluding that (1) the clot formation takes shorter time than the control; (2) there is a significant difference among the different concentrations thereby, the higher the concentration; and, (3) among all the different volume of blood used, 4mL of blood, has the most potent activity in inducing the clotting activity. |
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