Characterization of Philippine drug-susceptible and multi-drug resistant mycobacterium tuberculosis isolates through combined 15-locus MIRU-VNTR genotyping and mutation analysis of drug resistance genes

• Main Authors: Pastor, Crist John M., Tan-Liu, Nelia S., Barzaga, Maria Teresa A., Defensor, Dario D., Romano, Christopher T., Dela Cruz, Elsie Marie B., Chung, Francisco S., Jr., Caoili, Salvador Eugenio C., Heralde, Francisco M., III
• Format: text
• Published: Animo Repository 2022
• Subjects: Drug resistance in microorganisms—Genetic aspects; Multidrug-resistant tuberculosis; Mycobacterium tuberculosis; Chemistry; Medicinal-Pharmaceutical Chemistry
• Online Access: https://animorepository.dlsu.edu.ph/faculty_research/6094
• Institution: De La Salle University

Molecular genotyping, an important strategy to characterize bacterial strains infecting patients, allows identification of M. tuberculosis (MTb) complex members with varying responses to anti-mycobacterial therapy. M. tuberculosis Interspersed Repeating Units – Variable Number of Tandem Repeats (MIR...