Regression analysis on the chemical descriptors of a selected class of DPP4 inhibitors

• المؤلفون الرئيسيون: Janairo, Jose Isagani B., Co, Frumencio F., Janairo, Gerardo C., Yu, Derrick Ethelbhert C.
• التنسيق: text
• منشور في: Animo Repository 2010
• الموضوعات: CD26 antigen—Inhibitors; Chemistry
• الوصول للمادة أونلاين: https://animorepository.dlsu.edu.ph/faculty_research/6594
• المؤسسة: De La Salle University

The activity of a selected class of DPP4 inhibitors was assessed using quantum-chemical and physical descriptors. Using multiple linear regression model, it was found that ΔE, LUMO energy, dipole, area, volume, molecular weight and ΔH are the significant descriptors that can adequately assess the ac...