Towards the synthesis of 2'-fluorinated pyrimidine-based nucleosides
The progress towards the development of a model system for late-stage fluorination of pyrimidine-based nucleosides is described in this paper. The synthesis involved the introduction of a cyclic protecting group on the 3' - and 5' -hydroxyls of a ribose sugar that locks its conformation an...
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Main Authors: | , , |
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Format: | text |
Published: |
Animo Repository
2016
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Online Access: | https://animorepository.dlsu.edu.ph/faculty_research/8874 |
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Institution: | De La Salle University |