Cystic Fibrosis Transmembrane Conductance Regulator Protein Modulators in Children and Adolescents with Different CF Genotypes-Systematic Review and Meta-Analysis

• المؤلفون الرئيسيون: Hamdan, Alaa Hassan Yousif, Zakaria, Faiza, Pormento, Maria Kezia Lourdes, Lawal, Odunayo Susan, Opiegbe, Adaugo, Zahid, Samina, Guntipalli, Prathima, Nasr, Ujala, Rizvi, Syed Asad Ha San
• التنسيق: text
• منشور في: Archīum Ateneo 2024
• الموضوعات: CFTR protein modulators; conductance; Cystic fibrosis; elexacaftor; ivacaftor; meta-analysis; tezacaftor
• الوصول للمادة أونلاين: https://archium.ateneo.edu/asmph-pubs/119
• المؤسسة: Ateneo De Manila University

Objective: To determine the efficacy of the first triple CFTR protein modulators in children and adolescents with cystic fibrosis. Methods: Systematic review and meta-analysis were conducted, following PRISMA guidelines. The following databases were searched extensively: PubMed/Medline, Clinical tri...