Mechanistic aspects of the nickel‐catalyzed addition reaction of alkenyl‐zirconium reagents to cyclopropyl ketones

• Main Authors: Loots, Melanie J, Dayrit, Fabian M, Schwartz, Jeffrey
• Format: text
• Published: Archīum Ateneo 1980
• Subjects: Chemistry; Organic Chemistry
• Online Access: https://archium.ateneo.edu/chemistry-faculty-pubs/118; https://onlinelibrary.wiley.com/doi/abs/10.1002/bscb.19800891015
• Institution: Ateneo De Manila University

Nickel‐catalyzed addition of alkenylzirconium species to cyclopropyl ketones proceeds by an electron transfer mechanism. One‐electron reduction of the substrate leads to a ketyl which may either couple to give the 1, 2‐addition product or undergo a second one‐electron reduction, followed by rearrang...