Monitoring of Vancomycin in Human Plasma via Portable Microchip Electrophoresis With Contactless Conductivity Detector and Multi-Stacking Strategy

• Main Authors: Chong, Kah Chun, Thang, Lee Yien, Quirino, Joselito P, See, Hong Heng
• Format: text
• Published: Archīum Ateneo 2017
• Subjects: Micelle-to-solvent stacking; Field-enhance sample injection; Microchip electrophoresis; Vancomycin; Contactless conductivity detection; Analytical, Diagnostic and Therapeutic Techniques and Equipment; Chemistry
• Online Access: https://archium.ateneo.edu/chemistry-faculty-pubs/176; https://www.sciencedirect.com/science/article/pii/S002196731730047X
• Institution: Ateneo De Manila University

A portable microchip electrophoresis (MCE) coupled with on-chip contactless conductivity detection (C4D) system was evaluated for the determination of vancomycin in human plasma. In order to enhance the detection sensitivity, a new online multi-stacking preconcentration technique based on field-enha...