Amitriptyline Sequestration by Unmodified and Modified Microcrystalline Cellulose: A Potential Treatment for Drug Overdosing

Microcrystalline cellulose (MCC) was studied as a sequestrant of amitriptyline from its aqueous solution. Microcrystalline cellulose could adsorb 74% amitriptyline from pH 7.4 buffer solution in 2 h at room temperature. It was observed that the amount of amitriptyline as well as the equilibration ti...

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Bibliographic Details
Main Authors: Chakraborty, Soma, Bartolome, Adrienne Nicole S., Aguilar, Francisgerard A.
Format: text
Published: Archīum Ateneo 2023
Subjects:
MCC
NCC
Online Access:https://archium.ateneo.edu/chemistry-faculty-pubs/206
https://doi.org/10.1504/IJNBM.2023.132508
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Institution: Ateneo De Manila University