The Lipid-Heart Hypothesis and the Keys Equation Defined the Dietary Guidelines but Ignored the Impact of Trans-Fat and High Linoleic Acid Consumption

• Main Authors: Newport, Mary T, Dayrit, Fabian M
• Format: text
• Published: Archīum Ateneo 2024
• Subjects: Ancel Keys; cholesterol; dietary guidelines; heart disease; lipid–heart hypothesis; polyunsaturated fat; saturated fat; trans-fat; Cardiovascular Diseases; Diseases; Life Sciences; Medicine and Health Sciences; Molecular, Genetic, and Biochemical Nutrition; Nutrition
• Online Access: https://archium.ateneo.edu/chemistry-faculty-pubs/214; https://archium.ateneo.edu/context/chemistry-faculty-pubs/article/1214/viewcontent/nutrients_16_01447.pdf
• Institution: Ateneo De Manila University

In response to a perceived epidemic of coronary heart disease, Ancel Keys introduced the lipid-heart hypothesis in 1953 which asserted that high intakes of total fat, saturated fat, and cholesterol lead to atherosclerosis and that consuming less fat and cholesterol, and replacing saturated fat with...