Access to oxoquinoline heterocycles by N-heterocyclic carbene catalyzed ester activation for selective reaction with an enone

Access to oxoquinoline heterocycles by N-heterocyclic carbene catalyzed ester activation for selective reaction with an enone

Organocatalytic ester activation is developed for a highly selective cascade reaction between saturated esters and amino enones. The reaction involves activation of the β-carbon atom of the ester as a key step. This method allows a single-step access to multicyclic oxoquinoline-type heterocycles wit...

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Main Authors: Fu, Zhenqian, Jiang, Ke, Zhu, Tingshun, Torres, Jaume, Chi, Robin Yonggui
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2014
Subjects:
DRNTU::Science::Chemistry::Inorganic chemistry::Cyclic compounds
Online Access:https://hdl.handle.net/10356/100042
http://hdl.handle.net/10220/19652
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1000422020-03-07T12:18:06Z Access to oxoquinoline heterocycles by N-heterocyclic carbene catalyzed ester activation for selective reaction with an enone Fu, Zhenqian Jiang, Ke Zhu, Tingshun Torres, Jaume Chi, Robin Yonggui School of Biological Sciences School of Physical and Mathematical Sciences DRNTU::Science::Chemistry::Inorganic chemistry::Cyclic compounds Organocatalytic ester activation is developed for a highly selective cascade reaction between saturated esters and amino enones. The reaction involves activation of the β-carbon atom of the ester as a key step. This method allows a single-step access to multicyclic oxoquinoline-type heterocycles with high enantiomeric ratios. 2014-06-11T03:54:35Z 2019-12-06T20:15:40Z 2014-06-11T03:54:35Z 2019-12-06T20:15:40Z 2014 2014 Journal Article Fu, Z., Jiang, K., Zhu, T., Torres, J., & Chi, Y. R. (2014). Access to Oxoquinoline Heterocycles by N-Heterocyclic Carbene Catalyzed Ester Activation for Selective Reaction with an Enone. Angewandte Chemie International Edition, 53(25), 6506–6510. 1433-7851 https://hdl.handle.net/10356/100042 http://hdl.handle.net/10220/19652 10.1002/anie.201402620 179608 en Angewandte chemie international edition © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
topic DRNTU::Science::Chemistry::Inorganic chemistry::Cyclic compounds
spellingShingle DRNTU::Science::Chemistry::Inorganic chemistry::Cyclic compounds
Fu, Zhenqian
Jiang, Ke
Zhu, Tingshun
Torres, Jaume
Chi, Robin Yonggui
Access to oxoquinoline heterocycles by N-heterocyclic carbene catalyzed ester activation for selective reaction with an enone
description Organocatalytic ester activation is developed for a highly selective cascade reaction between saturated esters and amino enones. The reaction involves activation of the β-carbon atom of the ester as a key step. This method allows a single-step access to multicyclic oxoquinoline-type heterocycles with high enantiomeric ratios.
author2 School of Biological Sciences
author_facet School of Biological Sciences
Fu, Zhenqian
Jiang, Ke
Zhu, Tingshun
Torres, Jaume
Chi, Robin Yonggui
format Article
author Fu, Zhenqian
Jiang, Ke
Zhu, Tingshun
Torres, Jaume
Chi, Robin Yonggui
author_sort Fu, Zhenqian
title Access to oxoquinoline heterocycles by N-heterocyclic carbene catalyzed ester activation for selective reaction with an enone
title_short Access to oxoquinoline heterocycles by N-heterocyclic carbene catalyzed ester activation for selective reaction with an enone
title_full Access to oxoquinoline heterocycles by N-heterocyclic carbene catalyzed ester activation for selective reaction with an enone
title_fullStr Access to oxoquinoline heterocycles by N-heterocyclic carbene catalyzed ester activation for selective reaction with an enone
title_full_unstemmed Access to oxoquinoline heterocycles by N-heterocyclic carbene catalyzed ester activation for selective reaction with an enone
title_sort access to oxoquinoline heterocycles by n-heterocyclic carbene catalyzed ester activation for selective reaction with an enone
publishDate 2014
url https://hdl.handle.net/10356/100042
http://hdl.handle.net/10220/19652
_version_ 1681042213841141760

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