Complex polymorphisms in the plasmodium falciparum multidrug resistance protein 2 gene and its contribution to antimalarial response

Plasmodium falciparum has the capacity to escape the actions of essentially all antimalarial drugs. ATP-binding cassette (ABC) transporter proteins are known to cause multidrug resistance in a large range of organisms, including the Apicomplexa parasites. P. falciparum genome analysis has revealed t...

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Bibliographic Details
Main Authors: Veiga, Maria Isabel, Osório, Nuno S., Ferreira, Pedro Eduardo, Franzén, Oscar, Dahlstrom, Sabina, Lum, J. Koji, Nosten, Francois, Gil, José Pedro
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10356/100186
http://hdl.handle.net/10220/25681
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Institution: Nanyang Technological University
Language: English