Thermoacoustic resonance effect and circuit modelling of biological tissue

• Main Authors: Gao, Fei, Zheng, Yuanjin, Feng, Xiaohua, Ohl, Claus-Dieter
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/100405; http://hdl.handle.net/10220/10992
• Institution: Nanyang Technological University

In this letter, thermoacoustic resonance effect is predicted from theoretical analysis with series resistor-inductor-capacitor resonance circuit model and then observed experimentally using muscle tissue illuminated by multi-pulse microwave source. Through model fitting, the circuit parameters are extracted to characterize quantitatively the resonant response of the tissue. Coherent demodulation is applied to obtain the enhanced signal-to-noise ratio and spatial information by treating tissue as a communication channel. This physical phenomenon shows significantly higher sensitivity than conventional single microwave pulse induced thermoacoustic effect, enabling the potential design of low-power thermoacoustic imaging device for portable and on-site diagnosis.