The role of toll-like receptor 9 (TLR9) in autoimmunity : an examination into the relationship between gut microbiota and TLR9 in Systemic Lupus Erythematosus (SLE)

• 主要作者: Yasuga, Hiroko
• 其他作者: Anna-Marie Fairhurst
• 格式: Theses and Dissertations
• 語言: English
• 出版: 2019
• 主題: DRNTU::Science::Biological sciences::Microbiology::Immunology
• 在線閱讀: https://hdl.handle.net/10356/100426; http://hdl.handle.net/10220/48587

SLE is a complex autoimmune disease characterized by the production of anti-nuclear autoantibodies in a breakdown of self-tolerance. TLR9 is a receptor which recognises microorganism-associated unmethylated DNA. It is located in the endocytic pathway in B cells, dendritic cells (DCs), plasmacytoid D...