LSPR biomolecular assay with high sensitivity induced by aptamer–antigen–antibody sandwich complex

• Main Authors: Guo, Longhua, Kim, Dong-Hwan
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2013
• Online Access: https://hdl.handle.net/10356/100485; http://hdl.handle.net/10220/11078
• Institution: Nanyang Technological University

Herein we demonstrate a sensitive approach for protein detection based on peak shifts of localized surface plasmon resonance (LSPR) induced by aptamer–antigen–antibody sandwich structures. The applicability of the proposed method is demonstrated using human α-thrombin as a model analyte. While the b...