Cytotoxic triosmium carbonyl clusters : a structure-activity relationship study

• Main Authors: Top, Siden, Vessières, Anne, Leong, Weng Kee, Lee, Shirley Hui Zhi
• 其他作者: School of Physical and Mathematical Sciences
• 格式: Article
• 語言: English
• 出版: 2014
• 主題: DRNTU::Science::Biological sciences::Biochemistry
• 在線閱讀: https://hdl.handle.net/10356/100836; http://hdl.handle.net/10220/19690

A structure–activity relationship (SAR) study of the triosmium carbonyl cluster Os3(CO)10(NCCH3)2 was carried out with a series of clusters of the general formula Os3(CO)12−nLn, cationic osmium clusters and a hemi-labile maltolato-Os cluster. The SAR results showed that good solubility in DMSO and a...