Cytotoxic triosmium carbonyl clusters : are proteins the target?

The interaction of the cytotoxic triosmium carbonyl cluster Os3(CO)10(NCMe)2, 1 with different amino acids and oligopeptides was examined with regard to its selectivity towards the different residues. It was found that 1 was reactive to cysteine, glutamic acid, aspartic acid, glutamine and asparagin...

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Bibliographic Details
Main Author: Lee, Jia Ying
Other Authors: School of Physical and Mathematical Sciences
Format: Theses and Dissertations
Language:English
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/10356/55376
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Institution: Nanyang Technological University
Language: English