Rhodium-catalyzed C—H alkynylation of arenes at room temperature

The rhodium(III)-catalyzed ortho C[BOND]H alkynylation of non-electronically activated arenes is disclosed. This process features a straightforward and highly effective protocol for the synthesis of functionalized alkynes and represents the first example of merging a hypervalent iodine reagent with...

Full description

Saved in:
Bibliographic Details
Main Authors: Feng, Chao, Loh, Teck-Peng
Other Authors: School of Physical and Mathematical Sciences
Format: Article
Language:English
Published: 2014
Subjects:
Online Access:https://hdl.handle.net/10356/100874
http://hdl.handle.net/10220/19640
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English
id sg-ntu-dr.10356-100874
record_format dspace
spelling sg-ntu-dr.10356-1008742020-03-07T12:34:50Z Rhodium-catalyzed C—H alkynylation of arenes at room temperature Feng, Chao Loh, Teck-Peng School of Physical and Mathematical Sciences DRNTU::Science::Chemistry::Organic chemistry The rhodium(III)-catalyzed ortho C[BOND]H alkynylation of non-electronically activated arenes is disclosed. This process features a straightforward and highly effective protocol for the synthesis of functionalized alkynes and represents the first example of merging a hypervalent iodine reagent with rhodium(III) catalysis. Notably, this reaction proceeds at room temperature, tolerates a variety of functional groups, and more importantly, exhibits high selectivity for monoalkynylation. 2014-06-10T08:30:39Z 2019-12-06T20:29:34Z 2014-06-10T08:30:39Z 2019-12-06T20:29:34Z 2014 2014 Journal Article Feng, C., & Loh, T.-P. (2014). Rhodium-Catalyzed C—H Alkynylation of Arenes at Room Temperature. Angewandte Chemie, 126(10), 2760-2764. 0044-8249 https://hdl.handle.net/10356/100874 http://hdl.handle.net/10220/19640 10.1002/ange.201309198 en Angewandte chemie © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
institution Nanyang Technological University
building NTU Library
country Singapore
collection DR-NTU
language English
topic DRNTU::Science::Chemistry::Organic chemistry
spellingShingle DRNTU::Science::Chemistry::Organic chemistry
Feng, Chao
Loh, Teck-Peng
Rhodium-catalyzed C—H alkynylation of arenes at room temperature
description The rhodium(III)-catalyzed ortho C[BOND]H alkynylation of non-electronically activated arenes is disclosed. This process features a straightforward and highly effective protocol for the synthesis of functionalized alkynes and represents the first example of merging a hypervalent iodine reagent with rhodium(III) catalysis. Notably, this reaction proceeds at room temperature, tolerates a variety of functional groups, and more importantly, exhibits high selectivity for monoalkynylation.
author2 School of Physical and Mathematical Sciences
author_facet School of Physical and Mathematical Sciences
Feng, Chao
Loh, Teck-Peng
format Article
author Feng, Chao
Loh, Teck-Peng
author_sort Feng, Chao
title Rhodium-catalyzed C—H alkynylation of arenes at room temperature
title_short Rhodium-catalyzed C—H alkynylation of arenes at room temperature
title_full Rhodium-catalyzed C—H alkynylation of arenes at room temperature
title_fullStr Rhodium-catalyzed C—H alkynylation of arenes at room temperature
title_full_unstemmed Rhodium-catalyzed C—H alkynylation of arenes at room temperature
title_sort rhodium-catalyzed c—h alkynylation of arenes at room temperature
publishDate 2014
url https://hdl.handle.net/10356/100874
http://hdl.handle.net/10220/19640
_version_ 1681043397844926464