The acid free asymmetric intermolecular α-alkylation of aldehydes in fluorinated alcohols
The acid free asymmetric intermolecular α-alkylation of aldehydes with alcohols has been discovered using trifluoroethanol as solvent. This unprecedented system affords the enantioenriched functionalized primary alcohols (after NaBH4 reduction) in high yields and good to excellent enantioselectiviti...
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| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
2013
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| Online Access: | https://hdl.handle.net/10356/101016 http://hdl.handle.net/10220/11102 |
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| Institution: | Nanyang Technological University |
| Language: | English |
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