Optical manipulation of biological cell without measurement of cell velocity
Optical tweezer is a useful tool for non-contact micromanipulation tasks because it can manipulate biological cells precisely without causing damage to the cells. In many optical manipulation techniques, the measurement of the velocity of the cell is necessary. Since it is difficult to measure t...
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| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/101652 http://hdl.handle.net/10220/18882 |
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| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | Optical tweezer is a useful tool for non-contact
micromanipulation tasks because it can manipulate biological
cells precisely without causing damage to the cells. In many
optical manipulation techniques, the measurement of the velocity
of the cell is necessary. Since it is difficult to measure the
velocity of the cell, the velocity information is usually obtained
by differentiating the position of the cell in image space, which
may result in degraded performance of the control system due
to estimation error and the noises induced in differentiation.
In this paper, an adaptive observer technique is proposed for
optical manipulation of cell with a low Reynolds’ number,
without measurement of the velocity of the cell. By using
the proposed observer technique, a desired position input of
the laser beam without measurement of the velocity of the
cell is also developed. The stability of closed-loop system is
analyzed by using Lyapunov-like method. Experimental results
are presented to illustrate the performance of the proposed
control method. |
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