Novel pathophysiological markers are revealed by iTRAQ-based quantitative clinical proteomics approach in vascular dementia

• Main Authors: Lai, Mitchell K. P., Kalaria, Raj N., Chen, Christopher P., Datta, Arnab, Qian, Jingru, Chong, Ruifen, Francis, Paul, Sze, Siu Kwan
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/101828; http://hdl.handle.net/10220/18755
• Institution: Nanyang Technological University

Vascular dementia (VaD) is a leading cause of dementia in the elderly together with Alzheimer's disease with limited treatment options. Poor understanding of the pathophysiology underlying VaD is hindering the development of new therapies. Hence, to unravel its underlying molecular pathology, a...