Silicon waveguide multiplexed sensor array configuration for label-free biosensing applications

This article reviews different waveguide based architectures forlabel-free detection of biomolecules. Working principles of various configurationsare discussed with an emphasis on their sensing principle and sensitivity. Later part of the article demonstrates a silicon waveguide Bragg grating resona...

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Main Authors: Prabhathan, Patinharekandy, Murukeshan, Vadakke Matham
Other Authors: School of Mechanical and Aerospace Engineering
Format: Article
Language:English
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10356/101866
http://hdl.handle.net/10220/25693
http://journal.iisc.ernet.in/index.php/iisc/article/view/4512
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-1018662023-03-04T17:19:54Z Silicon waveguide multiplexed sensor array configuration for label-free biosensing applications Prabhathan, Patinharekandy Murukeshan, Vadakke Matham School of Mechanical and Aerospace Engineering Rolls-Royce@NTU Corporate Lab DRNTU::Engineering::Mechanical engineering::Bio-mechatronics This article reviews different waveguide based architectures forlabel-free detection of biomolecules. Working principles of various configurationsare discussed with an emphasis on their sensing principle and sensitivity. Later part of the article demonstrates a silicon waveguide Bragg grating resonator array as a highly sensitive refractive index sensor device for multiplexed detection of multi-analytes. Main features of the sensor element are discussed through numerical simulation, and proof-of concept device is demonstrated through micro fabrication. The proposed configuration of silicon waveguide based sensor array is expected to find potential application in portable chip based devices as highly sensitive multiplexed biosensors. Published version 2015-05-27T07:46:02Z 2019-12-06T20:46:00Z 2015-05-27T07:46:02Z 2019-12-06T20:46:00Z 2014 2014 Journal Article Prabhathan, P., & Murukeshan, V. M. (2014). Silicon waveguide multiplexed sensor array configuration for label-free biosensing applications. Journal of the Indian institute of science, 94(3), 273-282. https://hdl.handle.net/10356/101866 http://hdl.handle.net/10220/25693 http://journal.iisc.ernet.in/index.php/iisc/article/view/4512 en Journal of the Indian institute of science © 2014 Indian Institute of Science. This paper was published in Journal of the Indian Institute of Science and is made available as an electronic reprint (preprint) with permission of Indian Institute of Science. The paper can be found at the following URL: [http://journal.iisc.ernet.in/index.php/iisc/article/view/4512]. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper is prohibited and is subject to penalties under law. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Engineering::Mechanical engineering::Bio-mechatronics
spellingShingle DRNTU::Engineering::Mechanical engineering::Bio-mechatronics
Prabhathan, Patinharekandy
Murukeshan, Vadakke Matham
Silicon waveguide multiplexed sensor array configuration for label-free biosensing applications
description This article reviews different waveguide based architectures forlabel-free detection of biomolecules. Working principles of various configurationsare discussed with an emphasis on their sensing principle and sensitivity. Later part of the article demonstrates a silicon waveguide Bragg grating resonator array as a highly sensitive refractive index sensor device for multiplexed detection of multi-analytes. Main features of the sensor element are discussed through numerical simulation, and proof-of concept device is demonstrated through micro fabrication. The proposed configuration of silicon waveguide based sensor array is expected to find potential application in portable chip based devices as highly sensitive multiplexed biosensors.
author2 School of Mechanical and Aerospace Engineering
author_facet School of Mechanical and Aerospace Engineering
Prabhathan, Patinharekandy
Murukeshan, Vadakke Matham
format Article
author Prabhathan, Patinharekandy
Murukeshan, Vadakke Matham
author_sort Prabhathan, Patinharekandy
title Silicon waveguide multiplexed sensor array configuration for label-free biosensing applications
title_short Silicon waveguide multiplexed sensor array configuration for label-free biosensing applications
title_full Silicon waveguide multiplexed sensor array configuration for label-free biosensing applications
title_fullStr Silicon waveguide multiplexed sensor array configuration for label-free biosensing applications
title_full_unstemmed Silicon waveguide multiplexed sensor array configuration for label-free biosensing applications
title_sort silicon waveguide multiplexed sensor array configuration for label-free biosensing applications
publishDate 2015
url https://hdl.handle.net/10356/101866
http://hdl.handle.net/10220/25693
http://journal.iisc.ernet.in/index.php/iisc/article/view/4512
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