A new anticancer compound, Oblongifolin C, inhibits tumor growth and promotes apoptosis in HeLa cells through bax activation

Oblongifolin C (OC) was identified as a potent apoptosis inducer from an herbal plant, Garcinia yunnanensis, during our previous bioassay-guided drug screening. In this study, we investigated the signaling pathways through which OC activated apoptosis in HeLa cells. We also compared the IC50 values...

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Bibliographic Details
Main Authors: Feng, Chao, Zhou, Liying, Yu, Ting, Xu, Gang, Tian, Hong-Lei, Xu, Jin-Jie, Xu, Hong-Xi, Luo, Kathy Qian
Other Authors: School of Chemical and Biomedical Engineering
Format: Article
Language:English
Published: 2013
Online Access:https://hdl.handle.net/10356/102141
http://hdl.handle.net/10220/16943
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Institution: Nanyang Technological University
Language: English